Mr. Corleone Is Johnny's Godfather
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Tom Hagen: Mr. Corleone is Johnny's godfather. To the Italian people, that's a very religious, sacred, close relationship.
Jack Woltz: I respect it. He should ask me anything else. This favor I can't give him.
Tom Hagen: He never asks a second favor when he's been refused the first, understood?

Tom informs Jack that Johnny is The Don's godson and it is a very special relationship.